摘要 |
PCT No. PCT/JP92/01089 Sec. 371 Date Feb. 24, 1994 Sec. 102(e) Date Feb. 24, 1994 PCT Filed Aug. 27, 1992 PCT Pub. No. WO93/05027 PCT Pub. Date Mar. 18, 1993 <IMAGE> (I) A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomergaly, etc., wherein A represents a single bond, lower alkylene or carbonyl; B represents lower alkyl, aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; D represents aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; and E represents 4H-1,2,4-triazolyl, 1H-1,2,4-triazolyl or 1H-1,2,3-triazolyl.
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申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD. |
发明人 |
OKADA, MINORU;KAWAMINAMI, EIJI;YODEN, TORU;KUDOU, MASAFUMI;ISOMURA, YASUO |