发明名称 Triazolylated teritiary amine compound or salt thereof
摘要 PCT No. PCT/JP92/01089 Sec. 371 Date Feb. 24, 1994 Sec. 102(e) Date Feb. 24, 1994 PCT Filed Aug. 27, 1992 PCT Pub. No. WO93/05027 PCT Pub. Date Mar. 18, 1993 <IMAGE> (I) A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomergaly, etc., wherein A represents a single bond, lower alkylene or carbonyl; B represents lower alkyl, aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; D represents aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; and E represents 4H-1,2,4-triazolyl, 1H-1,2,4-triazolyl or 1H-1,2,3-triazolyl.
申请公布号 US5674886(A) 申请公布日期 1997.10.07
申请号 US19940199180 申请日期 1994.02.24
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD. 发明人 OKADA, MINORU;KAWAMINAMI, EIJI;YODEN, TORU;KUDOU, MASAFUMI;ISOMURA, YASUO
分类号 A61K31/425;A61P35/00;C07D249/04;C07D249/08;C07D401/12;C07D403/12;C07D521/00;C12N9/00;(IPC1-7):C07D249/08;A61K31/41 主分类号 A61K31/425
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