| 摘要 |
A novel transcription factor is provided, along with DNA encoding it, polypeptides which bind it, peptide fragments, mimetics, oligonucleotides, and methods employing these. The transcription factor, for which both mouse and human sequences are provided, has some similarity to E2F but, in contrast with E2F, is a transcriptional repressor. It is involved in cellular proliferation and is indicated to be an oncogen.
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