Antimicrobial dithiocarbamoyl quinolones

摘要

Antimicrobial dithiocarbamoyl quinolone compounds of the general formula: <IMAGE> wherein (1) A1, A2, A3, R1, R3, R4, and R6 form any of a variety of quinolone and related heterocyclic structures similar to those known in the art to have antimicrobial activity; and (2) (1) R1 is X, R3 is X, or both R1 and R3 are X; and X is the dithiocarbamate containing moiety; and pharmaceutically-acceptable salts and biohydrolyzable esters thereof, and hydrates thereof.