发明名称 GONADOTHROPINES WITH NON NATIVE DISULFIDE BRIDGES.
摘要 The present invention refers to gonadothropines consisting of a sub-unit, such gonadothropines comprising non native disulfide bridges, preferably disulfide bridges between non native sub-units. Gonadothropines according to the invention has an improved stability. The present invention also discloses pharmaceutical compositions comprising such gonadothropines.
申请公布号 MX9605048(A) 申请公布日期 1997.09.30
申请号 MX19960005048 申请日期 1996.10.23
申请人 AKZO NOBEL N.V. 发明人 PETER DIEDERIK JAN GROOTENHUIS;JUDITH CHRISTINA HEIKOOP
分类号 A61K38/04;A61K38/00;A61K38/24;C07K14/575;C07K14/59;(IPC1-7):C12N15/16 主分类号 A61K38/04
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