IMMUNOGENIC COMPOSITIONS COMPRISING PORPHYROMONAS GINGIVALIS PEPTIDES AND METHODS
摘要
Provided herein are methods and immunogenic compositions useful for protecting mammals from infection and pathology of P. gingivalis. Specifically, arginine-specific proteases of Porphyromonas gingivalis and peptides derived therefrom offer protection against infection. Immunogenic compositions comprising a 50 kDa arginine-specific protease, the high molecular weight complex or peptides from one of the foregoing proteins are capable of protecting against P. gingivalis infection and/or gingivitis and/or periodontitis caused thereby in mammals, including humans.
申请公布号
WO9734629(A1)
申请公布日期
1997.09.25
申请号
WO1997US04635
申请日期
1997.03.21
申请人
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;MOREHOUSE SCHOOL OF MEDICINE;POTEMPA, JAN;TRAVIS, JAMES;GENCO, CAROLINE, ATTARDO