| 发明名称 |
Steroidal glycosides for treating hypercholesterolemia |
| 摘要 |
<p>The invention provides spirostanyl glycosides of formula I,
<Chemistry id="chema01" num="0001"><Image id="ia01" he="44" wi="79" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein
<UnorderedLists id="ula01" listStyle="none" compact="compact"><ListItem>Q<Sup>1</Sup>, Q<Sup>4</Sup> and Q<Sup>5</Sup> are each methylene;</ListItem><ListItem>Q<Sup>2</Sup> is carbonyl;</ListItem><ListItem>Q<Sup>3</Sup> is
<Chemistry id="chema02" num="0002"><Image id="ia02" he="17" wi="128" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry></ListItem><ListItem>C<Sub>25</Sub> is (R); and</ListItem><ListItem>R<Sup>1</Sup> is a specified glycosidic group.</ListItem></UnorderedLists></p><p>The comopunds are useful in the treatment of hypercholesterolemia or atherosclerosis.</p> |
| 申请公布号 |
EP0796864(A2) |
申请公布日期 |
1997.09.24 |
| 申请号 |
EP19970200456 |
申请日期 |
1993.05.06 |
| 申请人 |
PFIZER INC. |
发明人 |
DENINNO, MICHAEL PAUL;MCCARTHY, PETER ANDREW |
| 分类号 |
A61K31/58;A61K31/704;A61P3/06;A61P9/10;C07J71/00;(IPC1-7):C07J71/00 |
主分类号 |
A61K31/58 |
| 代理机构 |
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| 地址 |
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