发明名称 |
T-cell receptor variable transcripts as disease related markers |
摘要 |
Methods are provided for determining relations between autoimmune degenerative diseases and specific variable regions of T-cell receptors as associated with the host HLA or T-cells associated with umbatting neoprofilerative diseases. By identifying the particular T-cell receptors which cause or are the disease in mammals, various prophylactic and therapeutic techniques may be employed for inhibiting the attack of the T-cell receptors on the native protein or tissue enhance the defense. In addition, individuals may be diagnosed as to their propensity for a particular autoimmune disease or the occurrence of such a disease.
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申请公布号 |
US5667967(A) |
申请公布日期 |
1997.09.16 |
申请号 |
US19930066325 |
申请日期 |
1993.05.21 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
STEINMAN, LAWRENCE;OKSENBERG, JORGE;BERNARD, CLAUDE |
分类号 |
C12Q1/68;(IPC1-7):C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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