发明名称 Cancer related antigen
摘要 A method of determining the prognosis of a solid tumor is provided, in which a sample from a patient bearing a tumor is assayed for the presence of a protein which is immunologically cross-reactive with the hpr gene product, but not with haptoglobin 1 or haptoglobin 2. Also provided is a method for preparing antibodies specific for this diagnostic marker which correlates with early relapse and metastasis of breast and other cancers. The marker can be detected using immunological methods employing antibodies specific for Hpr protein and not cross-reactive with haptoglobins 1 or 2.
申请公布号 US5665874(A) 申请公布日期 1997.09.09
申请号 US19950469005 申请日期 1995.06.05
申请人 JOHN HOPKINS UNIVERSITY 发明人 KUHAJDA, FRANCIS P.;PASTERNACK, GARY R.
分类号 A61K31/00;A61K31/20;A61K31/23;A61K31/335;A61K31/336;A61K31/34;A61K31/341;C07K14/47;C07K16/18;C07K16/30;C12N9/10;G01N33/574;(IPC1-7):C07H21/02;C07H21/04;C12P19/34;C12Q1/68 主分类号 A61K31/00
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