Diagnostic means that determines the genotype of a collagen gene of an individual is described. A polymorphism in the collagen gene correlates with predisposition to osteoporosis, so diagnosis of a predisposition is achieved using the diagnostic means. An isolated gene comprising the nucleotide substitution of the polymorphism is also described, as is a method of diagnosis based on the presence or absence of the polymorphism.
申请公布号
WO9732041(A1)
申请公布日期
1997.09.04
申请号
WO1997GB00569
申请日期
1997.02.28
申请人
GEMINI INTERNATIONAL HOLDINGS LIMITED;RALSTON, STUART, HAMILTON;GRANT, STRUAN, FREDERICK, AIRTH