| 摘要 |
<p>The invention concerns a compound of formula (I) wherein, for example: R1 is of the formula -NHC(=O)Rb wherein Rb is, for example, (1-4C)alkyl; R?2 and R3¿ are hydrogen or fluoro; D is O, S, SO, SO¿2? or NR?7; R4 and R5¿ are hydrogen, AR-oxymethy; R6 is hydrogen; ⊃A-B- is of the formula ⊃C=C(Ra)-, ⊃CHCHRa-, or ⊃C(OH)CHRa- (⊃represents two single bonds) wherein Ra is hydrogen or (1-4C)alkyl; R7 is hydrogen, AR or of the formula R?10CO-, R10SO¿2-, R?10CS-, RdOC(Re¿)=CH(C=O)-, RfC(=O)C(=O)-, RgN=C(Rh)C(=O)- or RiNHC(Rj)=CHC(=O)- or R?14CH(R13)(CH¿2)m-; wherein, for example, R10 is AR; R?d,Re,Rf,Rg,Rh,Ri and Rj¿ are (1-6C)alkyl; m is 0 or 1, R13 is cyano, R14 is hydrogen or (1-4C)alkyl; AR is phenyl; and pharmaceutically-acceptable salts thereof; processes for their preparation; pharmaceutical compositions containing them and their use as antibacterial agents.</p> |
