Water soluble fluorinated fatty acid sulfonate derivatives useful as magnetic resonance imaging agents

摘要

The present invention relates to improved imaging agents useful for 19F magnetic resonance imaging (MRI). More particularly, the present invention relates to fluorinated fatty acid sulfonate derivatives, such as those derived by reaction of fluorinated fatty acids with sulfonated compounds such as taurine analogs or isethionic acid analogs, which offer improved water solubility and biocompatibility.