发明名称 Copolymers with polyester polycarbonate blocks containing poly(caprolactone) segments, and use thereof for the preparation of biodegradable matrices.
摘要 The invention relates to block copolymers of general formula (I) -[-O-CO-O-A-O-CO-O-B-]a-(I) where a is an integer between 2 and 300 inclusive; A and B, which may be the same or different, are blocks which can be obtained by reaction between a bis(chloroformate) of oligomeric poly(caprolactone) and a polyester residue of formula (II) HO-[-R1-CO-O]x-[-R2-CO-O-]y-H (II) where R1 and R2, which may be the same or different, are each an aliphatic hydrocarbon residue with a linear or branched chain having from 1 to 4 carbon atoms; x and y are integers from 1 to 50, in any possible ratio from 0 to 1; the groups -R1-COO- and -R2-COO- being randomly distributed in the polyester residue.
申请公布号 ZA9701053(B) 申请公布日期 1997.08.25
申请号 ZA19970001053 申请日期 1997.02.10
申请人 ASTA MEDICA A.G. 发明人 PAOLO FERRUTI;MAURIZIO PENCO;ELISABETTA RANUCCI
分类号 A61K47/34;A61K9/20;C08G63/64;C08G63/87 主分类号 A61K47/34
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