发明名称 |
Genes codificadores do complexo desidrogenase de alfa-cetoácidos de cadeia ramificada a partir de streptomyces avermitilis |
摘要 |
The present invention relates to novel DNA sequences that encode for the branched-chain alpha-ketoacid dehydrogenase complex of an organism belonging to the genus Streptomyces and to novel polypeptides produced by the expression of such sequences. It also relates to novel methods of enhancing the production of natural avermectin, of producing a Streptomyces avermitilis bkd mutant and of producing novel avermectins through fermentation. |
申请公布号 |
BR9408337(A) |
申请公布日期 |
1997.08.19 |
申请号 |
BR19949408337 |
申请日期 |
1994.06.16 |
申请人 |
PFIZER, INC. |
发明人 |
CLAUDIO DANIEL DENOYA;KIM JONELLE STUTZMAN-ENGWALL |
分类号 |
C12N15/09;C07K14/36;C12N;C12N1/21;C12N5/10;C12N9/02;C12N15/00;C12N15/52;C12N15/53;C12N15/70;C12N15/76;C12P17/08;C12P17/18;C12P19/62;C12P21/02;C12R1/19;C12R1/465 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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