The present invention relates to monoclonal antibodies that define Oncostatin M. The monoclonal antibodies of the invention are capable of binding to Oncostatin M, inhibiting Oncostatin M receptor binding, and/or inhibiting Oncostatin M bioactivity. Such antibodies may be used to detect the presence of Oncostatin M and/or to modulate Oncostatin M bioactivities in an in vivo or in vitro system.
申请公布号
DE69123871(T2)
申请公布日期
1997.08.14
申请号
DE1991623871T
申请日期
1991.03.26
申请人
BRISTOL-MYERS SQUIBB COMPANY, NEW YORK, N.Y., US
发明人
RADKA, SUSAN F., SEATTLE, WASHINGTON 98103, US;LINSLEY, PETER S., SEATTLE, WASHINGTON 98119, US;SHOYAB, MOHAMMED, SEATTLE, WASHINGTON 98119, US