发明名称 TERPYRIDINE-PLATINUM(II) COMPLEXES
摘要 A new class of 2,2':6',2"-terpyridine-platinum (II) and substituted 2,2':6',2"terpyridine-platinum (II) complexes in which an N- or O- or halo nucleophile is the fourth ligand to platinum. The compounds are potent intercalators of DNA. Some have antitumour activity. Some have anti-parasitic activity. A new method of preparing the complexes involves reacting a Pt complex of 1,5cyclooctadiene with a 2,2':6',2"-terpyridine.
申请公布号 CA2241992(A1) 申请公布日期 1997.07.31
申请号 CA19972241992 申请日期 1997.01.24
申请人 ISIS INNOVATION LIMITED 发明人 LOWE, GORDON
分类号 C07D213/00;A61K31/00;A61K33/24;A61P33/00;A61P33/10;A61P35/00;C07D213/06;C07F15/00;C07H19/04;C07H21/00;(IPC1-7):C07F15/00;C07H23/00;A61K31/70 主分类号 C07D213/00
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