发明名称 USE OF [R-(Z)]-ALPHA-(METHOXYIMINO)-ALPHA-(1-AZABICYCLO [2.2.2] OCT-3-YL) ACETONITRILE TO REDUCE AMYLOID BETA A4 FORMATION IN ALZHEIMER'S DISEASE.
摘要 <p>A method of enhancing amyloid precursor protein processing along a non-amyloidogenic pathway in patients suffering from, or at risk of developing, Alzheimer's disease and a method of treatment or prophylaxis of Alzheimer's disease by reducing 'beta'A4 production in patients suffering from, or at risk of developing, Alzheimer's disease comprising administering to the patient an effective, non-toxic amount of an acetonitrile compound, use of the compound in preparation of a medicament for use in the method and a composition for use in the method.</p>
申请公布号 MX9703077(A) 申请公布日期 1997.07.31
申请号 MX19970003077 申请日期 1995.10.17
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 ROGER EDWARD MARKWELL;JULIE HAWKINS;CAROL WENDY GRAY
分类号 C07D453/02;A61K31/435;A61K31/439;A61P25/28;(IPC1-7):A61K31/435 主分类号 C07D453/02
代理机构 代理人
主权项
地址