| 摘要 |
PCT No. PCT/EP96/00363 Sec. 371 Date Jun. 27, 1997 Sec. 102(e) Date Jun. 27, 1997 PCT Filed Jan. 23, 1996 PCT Pub. No. WO96/23784 PCT Pub. Date Aug. 8, 1996The present invention concerns the compounds of formula the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein the dashed line designates an optional bond; R1 and R2 are each independently hydrogen, halogen, C1-6alkyl or C1-6alkyloxy; R3 and R4 are each independently hydrogen, C1-6alkyl, phenyl or phenyl substituted with one, two or three substituents selected from halo, hydroxy, nitro, cyano, trifluoromethyl, C1-6alkyl, C1-6alkyloxy, C1-6alkylthio, mercapto, amino, mono- and di(C1-6alkyl)-amino, carboxyl, C1-6alkyloxycarbonyl and C1-6alkylcarbonyl; Alk is C1-4alkanediyl; D is a pyrimidinone, piperidone or a benzimidozolidinone; having antipsychotic activity; their preparation, compositions containing them and their use as a medicine. |
