发明名称 |
Producing immunogenic constructs using soluble carbohydrates activated via organic cyanylating reagents |
摘要 |
The invention relates to a process for producing an immunogenic construct comprising activating at least one first carbohydrate-containing moiety with CDAP, and covalently joining the activated first moiety to a second moiety. Preferably, the first moiety is a polysaccharide and the second moiety is a protein. Immunogenic constructs are prepared by this process using either direct or indirect conjugation of the first and second moieties.
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申请公布号 |
US5651971(A) |
申请公布日期 |
1997.07.29 |
申请号 |
US19950408717 |
申请日期 |
1995.03.22 |
申请人 |
HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE |
发明人 |
LEES, ANDREW |
分类号 |
A61K39/385;A61K47/48;(IPC1-7):A61K39/385;C07K17/00 |
主分类号 |
A61K39/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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