发明名称 Thiol derivatives with metallopeptidase inhibitory activity
摘要 Compounds of formula (I), wherein R, R1, R2, and R3 have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
申请公布号 AU1301897(A) 申请公布日期 1997.07.28
申请号 AU19970013018 申请日期 1996.12.17
申请人 ZAMBON GROUP S.P.A. 发明人 FRANCO PELLACINI;MARIO FANTUCCI;GABRIELE NORCINI;STEFANO ROMAGNANO;FRANCESCO SANTANGELO;CLAUDIO SEMERARO
分类号 A61K31/00;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/425;A61K31/426;A61K31/44;A61K31/4427;A61K31/4439;A61K31/495;A61K31/505;A61P9/00;A61P43/00;C07D213/55;C07D239/26;C07D241/12;C07D277/20;C07D277/30;C07D307/54;C07D333/24;C07D417/12 主分类号 A61K31/00
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