| 发明名称 |
BIOCONJUGATES OF MANGANESE COMPLEXES AND THEIR APPLICATION AS CATALYSTS |
| 摘要 |
Bioconjugates of low molecular weight mimics of superoxide dismutase (SOD) represented by formula (I), wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, R'9, X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, such as ischemic/reperfusion injury, stroke, atherosclerosis, and all other conditions of oxidant-induced tissue damage or injury. |
| 申请公布号 |
WO9706824(A3) |
申请公布日期 |
1997.07.03 |
| 申请号 |
WO1996US12767 |
申请日期 |
1996.08.14 |
| 申请人 |
MONSANTO COMPANY;NEUMANN, WILLIAM, L.;RILEY, DENNIS, P.;WEISS, RANDY, H.;HENKE, SUSAN, L.;LENNON, PATRICK, J.;ASTON, KARL, W. |
发明人 |
NEUMANN, WILLIAM, L.;RILEY, DENNIS, P.;WEISS, RANDY, H.;HENKE, SUSAN, L.;LENNON, PATRICK, J.;ASTON, KARL, W. |
| 分类号 |
A61K47/48;A61K49/06;C07D259/00;C07F13/00 |
主分类号 |
A61K47/48 |
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