发明名称 NEW N-ARYL AND N-HETEROARYLUREA DERIVATIVES AS INHIBITORS OF ACYL COENZYME A: CHOLESTEROL ACYL TRANSFERASE (ACAT)
摘要 A compound of formula (I), the pharmaceutically acceptable salts thereof, wherein Q, R17, R18 and R1 are as defined below. The compounds of formula (I) are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.
申请公布号 CA2134359(C) 申请公布日期 1997.07.01
申请号 CA19932134359 申请日期 1993.04.20
申请人 PFIZER INC. 发明人 HAMANAKA, ERNEST S.
分类号 C07D239/42;A61K31/00;A61K31/38;A61K31/381;A61K31/44;A61K31/4418;A61K31/4433;A61K31/47;A61P3/06;A61P9/10;C07C275/00;C07C275/28;C07C335/06;C07C335/14;C07D213/60;C07D213/75;C07D215/38;C07D239/58;C07D333/58;C07D333/66;C07D409/12;(IPC1-7):C07D213/75;C07D471/04;A61K31/17;C07D217/22;A61K31/435;A61K31/505;C07D307/82 主分类号 C07D239/42
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