An anti-cocaine vaccine employs a cocaine hapten conjugated to a carrier protein. The anti-cocaine vaccine elicits an immune response which reduces the psychoactive effects of cocaine consumption by the production of anti-cocaine polyclonal antibodies. The antibodies may be employed in an ELISA test for assaying cocaine. The immune response elicited by the anti-cocaine vaccine produces antibody producing cells which may be isolated and cloned for producing anti-cocaine monoclonal antibodies.
申请公布号
WO9721451(A1)
申请公布日期
1997.06.19
申请号
WO1996US19982
申请日期
1996.12.16
申请人
THE SCRIPPS RESEARCH INSTITUTE;WIRSCHING, PETER;JANDA, KIM, D.