发明名称 CYTOKINE AND HEMOPOIETIC FACTOR ENDOGENOUS PRODUCTION ENHANCER AND METHODS OF USE THEREOF
摘要 The invention relates to medicine, in particular to pharmacology and therapy. According to the invention method of stimulating endogenous production of cytokine and hemopoietic factors comprising introducing to a mammalian body in need of stimulation of cytokine or hemopoietic factor or both, an effective amount of oxidized glutathione, its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative, for a period of time to stimulate said endogenous production to obtain a therapeutic effect, wherein said oxidized glutathione, or/and its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative is introduced parenterally or topically. According to the invention, oxidized glutathione or/and its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative is introduced along with an extender of the half life of said oxidized glutathione or/and its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative.
申请公布号 CA2239874(A1) 申请公布日期 1997.06.19
申请号 CA19962239874 申请日期 1996.12.10
申请人 KOZHEMYAKIN, LEONID ANDREEVICH;BALAZOVSKY, MARK BORISOVICH 发明人 KOZHEMYAKIN, LEONID ANDREEVICH;BALAZOVSKY, MARK BORISOVICH
分类号 A61K47/06;A61K38/00;A61K38/06;A61K47/02;A61K47/20;A61K47/26;A61P31/00;A61P35/00;A61P37/06;A61P37/08;A61P43/00;(IPC1-7):A61K38/06;A61K38/08;A61K38/14;A61K47/48 主分类号 A61K47/06
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