| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject suppressant capable of exhibiting suppressant activity against early antigen induction, extremely easy in obtaining its raw material and useful as a health keeping material, etc., by compounding a specific compound as an active component. SOLUTION: This suppressant contains at least one kind selected from (A) isoimperatorin of formula I, (B) aurapten of formula II, (C) epoxyaurapten of formula III and (D) 5-[(3,7-dimethyl-6-epoxy-2-octenyl)oxy]psoralen of formula IV as an active component. Further, the active component can be obtained by adding water to pericarp of Citrus hassaku, etc., at room temperature, separating the obtained emulsified liquid by centrifuge and isolating and purifying the obtained pericarp oil. It is preferable administered at a daily dose of about 10-50mg per adult. |
