发明名称 |
KONDENSIERTE HETEROCYCLISCHE KETONDERIVATE, IHRE HERSTELLUNG UND IHRE VERWENDUNG |
摘要 |
<p>A compound of the formula: <CHEM> wherein R<1> is H or an optionally substituted hydrocarbon or acyl group; ring A is an optionally further substituted benzene ring; n is an integer of 1 to 10; R<2>, R<3> and R<4> are H or an optionally substituted hydrocarbon group; R<3> and R<4> may form an optionally substituted heterocyclic group, taken together with the adjacent nitrogen atom; k is an integer of 0 to 3; and m is an integer of 1 to 8; provided that when k=0 and m=2, n is an integer of not less than 2 or a pharmaceutically acceptable salt thereof, exhibiting excellent cholinesterase inhibitory activity and monoamine reuptake inhibitory activity, thus being useful as therapeutic/prophylactic medicaments of senile dementia.</p> |
申请公布号 |
AT154020(T) |
申请公布日期 |
1997.06.15 |
申请号 |
AT19930103614T |
申请日期 |
1993.03.06 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
GOTO, GIICHI;MIYAMOTO, MASAOMI;ISHIHARA, YUJI |
分类号 |
C07D209/08;C07D215/08;C07D223/16;C07D225/06;C07D401/04;C07D401/06;C07D401/12;C07D405/12;C07D417/12;C07D471/10;(IPC1-7):C07D401/06;C07D413/06;C07D403/06;C07D215/14;A61K31/445 |
主分类号 |
C07D209/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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