发明名称 STABLE VANCOMYCIN HYDROCHLORIDE SOLUTIONS
摘要 The present invention provides stable solutions of vancomycin hydrochloride comprising between about 0.5 % and about 12 % w/v vancomycin hydrochloride and between about 0.5 % and about 30 % v/v ethanol. These solutions are particularly useful for storage in a liquid state not requiring either freezing or freeze drying in order to maintain stability of the active agent. The present invention also provides a method of inhibiting degradation of vancomycin hydrochloride in a solution containing between about 0.5 % and about 12 % w/v vancomycin hydrochloride, said method comprising including between about 0.5 % and about 30 % v/v ethanol in said solution.
申请公布号 WO9719690(A1) 申请公布日期 1997.06.05
申请号 WO1996US18898 申请日期 1996.11.25
申请人 ELI LILLY AND COMPANY;ROBISON, ROBERT, L. 发明人 ROBISON, ROBERT, L.
分类号 A61K38/14;(IPC1-7):A61K38/00 主分类号 A61K38/14
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