发明名称 |
STABLE VANCOMYCIN HYDROCHLORIDE SOLUTIONS |
摘要 |
The present invention provides stable solutions of vancomycin hydrochloride comprising between about 0.5 % and about 12 % w/v vancomycin hydrochloride and between about 0.5 % and about 30 % v/v ethanol. These solutions are particularly useful for storage in a liquid state not requiring either freezing or freeze drying in order to maintain stability of the active agent. The present invention also provides a method of inhibiting degradation of vancomycin hydrochloride in a solution containing between about 0.5 % and about 12 % w/v vancomycin hydrochloride, said method comprising including between about 0.5 % and about 30 % v/v ethanol in said solution.
|
申请公布号 |
WO9719690(A1) |
申请公布日期 |
1997.06.05 |
申请号 |
WO1996US18898 |
申请日期 |
1996.11.25 |
申请人 |
ELI LILLY AND COMPANY;ROBISON, ROBERT, L. |
发明人 |
ROBISON, ROBERT, L. |
分类号 |
A61K38/14;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|