摘要 |
<p>This invention relates to a 8-trifluoromethylquinolinecaboxylic acid derivative represented by the following formula (I): <CHEM> (wherein R<1> represents a lower alkyl group, a halogeno-lower alkyl group or a cycloalkyl group, R<2> represents a phenyl group which may be substituted by R<0>, a 5-membered or 6-membered aromatic heteromonocyclic ring group containing 1 or 2 hetero atoms selected from N, O and S, which may be substituted by R<0>, or an aromatic heterocyclic fused ring group in which the said aromatic heteromonocyclic ring and a benzene ring are fused, R<0> represents a group selected from a halogen, a lower alkyl, a fluorine-substituted lower alkyl, a lower alkoxy or a lower alkylthio, R<3> represents hydrogen or a lower alkyl group, and m represents an integer of 2 or 3.> or a pharmaceutically acceptable salt thereof or an ester thereof.</p> |