发明名称 |
Methods of use of serine protease variants having peptide ligase activity |
摘要 |
The invention relates to serine protease variants derived from precursor serine proteases via recombinant and/or chemical methods to form protease variants having improved peptide ligase activity. The invention also includes novel ligation substrates which in combination with the serine protease variants and a second ligation substrate are capable of forming a ligation product. The invention also relates to methods for forming such ligation products and the products formed thereby.
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申请公布号 |
US5629173(A) |
申请公布日期 |
1997.05.13 |
申请号 |
US19950386000 |
申请日期 |
1995.02.09 |
申请人 |
GENENTECH, INC. |
发明人 |
ABRAHMSEN, LARS;BURNIER, JOHN;WELLS, JAMES A.;JACKSON, DAVID Y. |
分类号 |
C07K14/61;C12N9/22;C12N9/54;C12P21/02;(IPC1-7):C12P21/06;C12P7/62;C12N9/56 |
主分类号 |
C07K14/61 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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