| 摘要 |
PROBLEM TO BE SOLVED: To obtain a therapeutic and prophylactic agent for atopic dermatitis containing an essence of seeds of a labiate basil. SOLUTION: This therapeutic and prophylactic agent for atopic dermatitis contains pulverized, chopped and dried seeds of a labiate basil, an extract separated from the processed material with a solvent (e.g. water or an alcohol) or a substance removed from the solvent and an essence which is a fractionated substance thereof as an active ingredient. The extraction is performed by adding the solvent in an amount of 1-20 times based on the seeds or their processed material thereto, then dipping the seeds, etc., therein at ambient temperature for several days or at a temperature near the boiling point of the solvent for several hours and, as necessary, subsequently removing an insoluble substance by filtration, etc. The extract is formulated into an oral administration agent, a parenteral injection or a percutaneous administration agent by further suitably blending optional ingredients therewith. The daily dose for an adult is 5-500mg divided into several portions in the case of the oral administration agent and 1-100mg for the parenteral injection. When the resultant formulation is percutaneously administered as a dermal preparation for external use, 0.01-10wt.% is blended in the dosage form and a proper amount thereof is daily applied to a lesion several times. |
