摘要 |
<p>The present invention provides compositions and various novel uses of the glucose transporter, GLUT-2. Included are methods of using GLUT-2 in cell killing, such as in negative selection and double selection protocols in vitro, in screening methods for identifying genes, promoters and substrates, and in cell killing in vivo, such as may be used in cancer treatment. Also provided are modified functional glucose transporters resistant to diabetic immune attack and methods of making and using such transporters.</p> |