发明名称 |
METHOD AND PREPARATIONS FOR STABILIZING BIOLOGICAL MATERIALSBY DRYING METHODS WITHOUT FREEZING |
摘要 |
The invention concerns a method of producing dry partially amorphous product s containing biological, in particular therapeutically active, material, the products comprising macroscopically homogeneous substance mixtures. The substance mixtures are selected from at least one substance of the group comprising: (i) carbohydrate or zwitterion with a polar residue and its derivatives; and (ii) zwitterion with an apolar residue and its derivatives. The method is characterized in that a solution of the biologically or therapeutically active material and substances (i) and (ii) is produced and dried at a product temperature above the freezing point of the solution. The invention further concerns novel substance mixtures obtained by the above method and their use in diagnostic or therapeutic processes.
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申请公布号 |
CA2235243(A1) |
申请公布日期 |
1997.05.01 |
申请号 |
CA19962235243 |
申请日期 |
1996.10.24 |
申请人 |
BOEHRINGER MANNHEIM GMBH |
发明人 |
WINTER, GERHARD;MATTERN, MARKUS |
分类号 |
A61K9/14;A61K38/00;A61K38/18;A61K38/19;A61K38/44;A61K47/18;A61K47/26;F26B5/04;(IPC1-7):A61K47/26;A61K49/00;A61K51/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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