Process for removing bile salts from a patient and compositions therefor

摘要

A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly crosslinked polymers characterized by a repeat unit having the formula (1) or copolymer thereof, where n is an integer; R1 is H or a C1-C8 alkyl group; M is or -Z-R2; Z is O, NR3, S, or (CH2)m; m=0-10; R3 is H or a C1-C8 alkyl group; and R2 is where p=0-10, and each R4, R5, and R6, independently, is H, a C1-C8 alkyl group, or an aryl group, the polymers being non-toxic and stable once ingested.