| 摘要 |
<p>A vascular permeation inhibitor, especially an inhibitor for, e.g., carcinomatous hydrothorax or carcinomatous ascites, which comprises an oxaspirooctane derivative represented by general formula (I) or a pharmacologically acceptable salt thereof, and a pharmacologically acceptable carrier, wherein R1 represents, e.g., lower alkylcarbamoyl or protected carbamoyl; R2 represents lower alkoxy; and R3 represents the group represented by formula (II).</p> |
