发明名称 |
CHIRAL SYNTHESIS OF 2-HYDROXY CARBOXYLIC ACIDS WITH A DEHYDROGENASE |
摘要 |
PCT No. PCT/EP95/02692 Sec. 371 Date May 29, 1997 Sec. 102(e) Date May 29, 1997 PCT Filed Jul. 7, 1995 PCT Pub. No. WO96/01892 PCT Pub. Date Jan. 25, 1996Inter alia, an enzyme, a 2-hydroxy carboxylic acid dehydrogenase, characterised in that it is obtainable from Lactobacillus delbrueckii ssp. Bulgaricus and in that it catalyses the production of (R)-hydroxy derivatives of 2-keto acids, which are unsubstituted in the 3-position, but which may be substituted in the 4-position or beyond is disclosed. |
申请公布号 |
EP0767832(A1) |
申请公布日期 |
1997.04.16 |
申请号 |
EP19950940911 |
申请日期 |
1995.07.07 |
申请人 |
GENZYME LIMITED |
发明人 |
HOLBROOK, JOSEPH, JOHN;WILLIS, CHRISTINE, LOUISE;JOHNSEN, KEYJI;HATELEY, MARTIN, JOHN |
分类号 |
C12N15/09;C12N9/04;C12N15/00;C12N15/53;C12P7/42;C12R1/19;C12R1/225 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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