摘要 |
FIELD: pharmacy technology. SUBSTANCE: invention proposes method of purification of vinblastine sulfate obtaining from Catharantus roseum by crystallization of technical product from two-four-component solvent mixture containing aliphatic alcohol, for example, ethanol, propanol, isopropanol, butanol, isobutanol, tert.-butanol, pentanol, isopentanol, hexanol, ethoxyethanol and chlorohydrocarbon, for example, methylene chloride or chloroform. EFFECT: improved method of purification. |