| 摘要 |
PCT No. PCT/FR93/00663 Sec. 371 Date Mar. 5, 1995 Sec. 102(e) Date Mar. 9, 1995 PCT Filed Jun. 30, 1993 PCT Pub. No. WO94/01390 PCT Pub. Date Jan. 20, 1994The present invention concerns a process for enantioselective catalytic hydrogenation of the ketone C=O double bond to a secondary alcohol function, said process using a neutral ruthenium complex as the catalyst and a compound containing a C=O group as the substrate to be hydrogenated, characterised in that it comprises hydrogenation of the substrate using a diallyl (diphosphino) ruthenium compound with formula <IMAGE> (I) where al preferably represents CH2CH=CH2 or CH2C(CH3)=CH2, Q represents a hydrocarbon bridge containing at least two catenary carbon atoms and which can contain one to four catenary heteroatoms selected from O, S, N and Si, R1 to R4 may be identical or different and each represents a C1-C18 alkyl, C5-C7 cycloalkyl or C6-C12 aryl group.
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