| 摘要 |
New 3-(w(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1-yl)alkyl)-3,4- dihydroquinazolin-2(1H)-one derivs. of formula (I) and their acid and base addn. salts are new. R1, R2 = H, halo, NH2, OH, NO2, CN, 1-6C alkyl, 1-6C alkoxy, CF3, OCF3, COOH, COOR4, CONH2, CONHR4, CONR4R5, SR4, SO2R4, OSO2CF3, NHCOR4, NHSO2R4 or -N(R4)2; R3 = H, 1-4C alkyl, -(CH2)pOH, -(CH2)pNH2, -(CH2)nCOOH, -(CH2)nCOOR4, -(CH2)nCONH2, -(CH2)nCONHOH, -(CH2)pSH, -(CH2)nSO3H, -(CH2)nSO2NH2, -(CH2)nSO2NHR4, (CH2)nSO2NR4R5, -(CH2)nCONHR4, -(CH2)nCONR4R5, -(CH2)pNHCOR4, -(CH2)pNHSO2R4, -(CH2)pOCOR4; R4,R5 = 1-4C alkyl; n = 1-4; p, m = 2-4.
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