CURCUMIN (DIFERULOYLMETHANE) INHIBITION OF NF kappa B ACTIVATION

摘要

The present invention provides a method of inhibiting the activation of the NF- kappa B transcription factor in an animal in need of such treatment comprising the step of administering to said animal a pharmacologically effective dose of curcumin. Also provided is a method of inhibiting the nuclear translocation of the p65 subunit of the NF- kappa B transcription factor in a cell or in an animal in need of such treatment comprising the step of administering to said animal a pharmacologically effective dose of curcumin.