| 发明名称 |
Process for making HIV protease inhibitors |
| 摘要 |
A process for making a clinically efficacious HIV protease inhibitor Compound J eliminates one step in its synthesis, by an improved, alternative synthesis of the 2(S)-4-picolyl-2-piperazine-t-butyl-carboxamide intermediate.
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| 申请公布号 |
US5612484(A) |
申请公布日期 |
1997.03.18 |
| 申请号 |
US19950443631 |
申请日期 |
1995.05.18 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ASKIN, DAVID;SAGER, JESS;ROSSEN, KAI;VOLANTE, RALPH P.;REIDER, PAUL J. |
| 分类号 |
C07D241/04;C07D401/06;C07D413/14;(IPC1-7):C07D401/06 |
主分类号 |
C07D241/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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