ANTINEOPLASTIC CHEMOTHERAPEUTIC OF PLANT ORIGIN, HAVING HIGH SELECTIVITY AND GREATLY REDUCED TOXICITY, AND PROCESS FOR THE PREPARATION THEREOF

摘要

PCT No. PCT/IT92/00057 Sec. 371 Date Jan. 28, 1993 Sec. 102(e) Date Jan. 28, 1993 PCT Filed May 22, 1992 PCT Pub. No. WO92/21359 PCT Pub. Date Dec. 10, 1992The invention relates to active principles having an antineoplastic action, extracted from plants of the family Pittosporacee, and to pharmaceutical preparations based on at least one of the substances or compositions to be found in said extracts. With respect to other known antitumoral drugs, these antineoplastic chemotherapeutic drugs show greater selectivity towards degenerated cells and a lower level of interference with the metabolism of healthy cells. The invention also extends to the process for extraction and separation of the components of the extracts and to their use for the preparation of antineoplastic drugs or drugs for the treatment of other pathologies.