发明名称 |
Antibacterial penem esters derivatives |
摘要 |
<p>Novel antibacterial penem esters are methyl (5R,6S)-6-Ä(R)-1-hydroxyethylÜ-2-Ä(R)-2-tetrahydrofurylÜ-penem-3-carbo xylates having at the 3-position an ester group of the formula -COOR in which R represents -CH2OCO-Y or -CH2-Z in which Y is a tetrahydrofuryl group; a tetrahydropyranyl group; a 1,3-dioxolanyl group; a 2-oxo-1,3-dioxolanyl group; or a 1,4-dioxanyl group and Z is a 5-(C6-C10 aryl or C7-C11 aralkyl)-2-oxo-1,3-dioxolen-4-yl group. Other substituted-methyl (5R,6S)-6- Ä(R)-1-hydroxyethylÜ-2-Ä(R)-2-tetrahydrofurylÜ-penem-3-carboxylates are disclosed.</p> |
申请公布号 |
EP0757050(A1) |
申请公布日期 |
1997.02.05 |
申请号 |
EP19960117054 |
申请日期 |
1991.08.16 |
申请人 |
SUNTORY LIMITED |
发明人 |
IWATA, HIROMITSU;TANAKA, RIE;NAKATSUKA, TAKASHI;ISHIGURO, MASAJI |
分类号 |
A61P31/04;C07D499/897;A61K31/43;A61K31/431;C07D499/04;C07D499/88;C07D499/887;C07D499/893;(IPC1-7):C07D499/88 |
主分类号 |
A61P31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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