发明名称 Thiazolidinediones and drugs containing them
摘要 PCT No. PCT/EP94/01619 Sec. 371 Date Nov. 21, 1995 Sec. 102(e) Date Nov. 21, 1995 PCT Filed May 19, 1994 PCT Pub. No. WO94/27995 PCT Pub. Date Dec. 8, 1994Compounds of formula I <IMAGE> (I) in which A denotes a carbocyclic ring with 5 or 6 carbon atoms or a heterocyclic ring with a maximum of 4 heteroatoms in which the heteroatoms can be the same or different and denote oxygen, nitrogen or sulphur and the heterocycles can if desired carry an oxygen atom on one or several nitrogen atoms, B denotes -CH=CH-, -N=CH-, -CH=N-, O or S, W denotes CH2, O, CH(OH), CO or -CH=CH-, X denotes S, O or NR2 in which the residue R2 is hydrogen or C1-C6 alkyl, Y is CH or N, R denotes naphthyl, pyridyl, furyl, thienyl or phenyl which if desired is mono- or disubstituted with C1-C3 alkyl, CF3, C1-C3 alkoxy, F, Cl or bromine, R1 denotes hydrogen or C1-C6 alkyl and n equals 1-3 as well as their tautomers, enantiomers, diastereomers and physiologically tolerated salts, processes for their production as well as pharmaceutical agents that contain these compounds for the treatment of diabetes.
申请公布号 US5599826(A) 申请公布日期 1997.02.04
申请号 US19950578561 申请日期 1995.11.21
申请人 BOEHRINGER MANNHEIM GMBH 发明人 MERTENS, ALFRED;WOLFF, HANS-PETER;FREUND, PETER
分类号 C07D277/20;A61K31/42;A61K31/425;A61K31/426;A61K31/427;A61P3/06;A61P3/10;C07D277/34;C07D417/06;C07D417/10;C07D417/12;C07D417/14;(IPC1-7):C07D417/12 主分类号 C07D277/20
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