GENETIC THERAPY EMPLOYING THE HHV-6A DERIVED TS GENE OR POLYPEPTIDE

摘要

The HHV-6 transcription suppressor (ts) gene acts at the level of transcription to shut-off expression of the HIV LTR promoter and of the H-ras gene, a gene whose mutational activation is associated with numerous human cancers. The ts gene is delivered to cells by a pharmaceutically acceptable vehicle and acts as either a preventative or therapeutical agent against cancer or against viral infections.