摘要 |
There is disclosed the use, as an agent in the treatment or the prevention of an autoimmune disease, of: (i) an agent having GM-1 binding activity, other than Ctx or Etx, or the B subunits of Ctx and Etx; or (ii) an agent having an effect on GM-1 mediated intracellular signalling events, but no GM-1 binding activity. These agents may also be used in the treatment of human T cell leukaemia, in the prevention of transplant rejection or GVHD or in a vaccination method for vaccinating a mammalian subject.
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申请人 |
UNIVERSITY OF BRISTOL;WILLIAMS, NEIL, ANDREW;HIRST, TIMOTHY, RAYMOND;NASHAR, TOUFIC, OSMAN |
发明人 |
WILLIAMS, NEIL, ANDREW;HIRST, TIMOTHY, RAYMOND;NASHAR, TOUFIC, OSMAN |