摘要 |
<p>A pyrazole compound of formula (I), wherein R?1 and R3¿ are the same or different and each is independently hydrogen, lower alkyl, ar(lower)alkyl, heterocyclic group, or aryl which may have one or more suitable substituent(s), R2 is hydrogen, lower alkyl, or ar(lower)alkyl which may have one or more suitable substituent(s), and R4 is hydrogen or lower alkyl, or a salt thereof. The pyrazole compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or the treatment of ischemic heart diseases (e.g. angina, etc.), peripheral vascular diseases (e.g. claudication, etc.), cerebral ischemia, migraine, diabetes, depression, Parkinson's disease, and the like.</p> |