摘要 |
Compounds of general formula (I), salts thereof or hydrates thereof wherein (a) represents (b) or (c), for example, the compounds (d) and (e), which are useful as a PGD2 antagonist and thus usable in, for example, a remedy for systemic mastocytosis or systemic mast cell activation disorders, a drug for bronchoconstriction, an antiasthmatic, a drug for allergic rhinitis agent, a drug for allergic conjunctivitis, a drug for urticaria, a remedy for ischemia reflow disorders or an antiinflammatory agent. It is particularly useful in the treatment of nasal occlusion.
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