发明名称 Antisense oligonucleotides directed against nucleic acids encoding NFKB transcription factor
摘要 The present invention is directed to oligodeoxynucleotides which are capable of hybridizing to genes which encode NF- kappa B. The oligodeoxyribonucleotides are antisense to NF kappa B genes and when hybridized prevent the production of NF kappa B transcription factor by the NF kappa B genes, and thereby provide a means for preventing cellular adhesion.
申请公布号 US5591840(A) 申请公布日期 1997.01.07
申请号 US19940328592 申请日期 1994.10.25
申请人 HOFFMANN-LA ROCHE INC. 发明人 NARAYANAN, RAMASWAMY;ROSEN, CRAIG A.
分类号 A61K31/70;A61K48/00;C12N15/09;C12N15/113;(IPC1-7):C07H21/04 主分类号 A61K31/70
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