发明名称 |
Antisense oligonucleotides directed against nucleic acids encoding NFKB transcription factor |
摘要 |
The present invention is directed to oligodeoxynucleotides which are capable of hybridizing to genes which encode NF- kappa B. The oligodeoxyribonucleotides are antisense to NF kappa B genes and when hybridized prevent the production of NF kappa B transcription factor by the NF kappa B genes, and thereby provide a means for preventing cellular adhesion.
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申请公布号 |
US5591840(A) |
申请公布日期 |
1997.01.07 |
申请号 |
US19940328592 |
申请日期 |
1994.10.25 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
NARAYANAN, RAMASWAMY;ROSEN, CRAIG A. |
分类号 |
A61K31/70;A61K48/00;C12N15/09;C12N15/113;(IPC1-7):C07H21/04 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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