发明名称 |
N-[Mercaptoacyl (amino acid or peptide ) ] compounds and S-lipophiIic aliphatic carbonyl derivatives thereof as antihypertensives |
摘要 |
N-[Mercaptoacyl(amino acid or peptide)] compounds and S-lipophilic aliphatic carbonyl derivatives thereof, and pharmaceutical compositions comprising such compounds, as well as the use of these compounds as antihypertensives by the inhibition of neutral endopeptidase and/or peptidyldipeptidase A are disclosed. Methods for preparing the such compounds and derivatives are disclosed also.
|
申请公布号 |
US5591891(A) |
申请公布日期 |
1997.01.07 |
申请号 |
US19940185563 |
申请日期 |
1994.01.24 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
FOURNIE-ZALUSKI, MARIE-CLAUDE;ROQUES, BERNARD-PIERRE |
分类号 |
A61K38/55;A61K38/00;A61P9/12;A61P43/00;C07K1/113;C07K5/06;C07K5/065;C07K14/81;(IPC1-7):C07C321/00 |
主分类号 |
A61K38/55 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|