发明名称 HUMAN NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR COMPOSITIONS AND METHODS EMPLOYING SAME
摘要 Nucleic acid molecules encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing the nucleic acid molecules, and methods for producing alpha and beta subunits are provided. In particular, nucleic acid molecules encoding .alpha.6 subunits and molecules encoding .beta.3 subunits of human neuronal nicotinic acetylcholine receptors are provided. In addition, combinations of a plurality of subunits, such as one or more of .alpha.1, .alpha.2, .alpha.3, .alpha.4, .alpha.5, .alpha.6 and/or .alpha.7 subunits in combination with one or more of .beta.3 subunits or such as one or more of .beta.2, .beta.3 and/or .beta.4 subunits in combination with an .alpha.6 subunit are provided.
申请公布号 CA2221311(A1) 申请公布日期 1996.12.27
申请号 CA19962221311 申请日期 1996.06.07
申请人 SIBIA NEUROSCIENCES, INC. 发明人 HARPOLD, MICHAEL M.;ELLIOTT, KATHRYN J.
分类号 C12N15/09;C07K14/705;C12N1/21;C12N5/10;C12N15/12;C12Q1/02;C12Q1/68;C12R1/91;(IPC1-7):C12N15/12;C07H21/04;G01N33/566 主分类号 C12N15/09
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