| 摘要 |
Reagents and methods are disclosed for modifying a fabric substrate in order to inactivate viruses, and particularly lipid-enveloped viruses, upon contac t. Such substrates can be modified by photochemically immobilizing hydrophilic polymers containing both quaternary ammonium groups and hydrocarbon chains, resulting in a localized surfactancy capable of disrupting lipid-enveloped viruses upon contact with the substrate. Substrates of the invention can be fabricated into the form of articles for medical and related use. |
